Loop Diuretic Administration in Patients with Acute Heart Failure and Reduced Systolic Function: Effects of Different Intravenous Diuretic Doses and Diuretic Response Measurements
نویسندگان
چکیده
منابع مشابه
Rationale and study design of intravenous loop diuretic administration in acute heart failure: DIUR‐AHF
AIMS Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown. The significance of worsening renal function occurrence during intravenous treatment is not clear enough. This trial aims to clarify all these features and contemplate whether continuous infusion is better than an intermittent strat...
متن کاملLoop diuretic efficiency: a metric of diuretic responsiveness with prognostic importance in acute decompensated heart failure.
BACKGROUND Rather than the absolute dose of diuretic or urine output, the primary signal of interest when evaluating diuretic responsiveness is the efficiency with which the kidneys can produce urine after a given dose of diuretic. As a result, we hypothesized that a metric of diuretic efficiency (DE) would capture distinct prognostic information beyond that of raw fluid output or diuretic dose...
متن کاملDiuretic strategies in patients with acute decompensated heart failure.
BACKGROUND Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use. METHODS In a prospective, double-blind, randomized trial, we assigned 308 patients with acute decompensated heart failure to receive furosemide administered intravenously by means of either a bolus every 12 hours or continu...
متن کاملRapid and Highly Accurate Prediction of Poor Loop Diuretic Natriuretic Response in Patients With Heart Failure.
BACKGROUND Removal of excess sodium and fluid is a primary therapeutic objective in acute decompensated heart failure and commonly monitored with fluid balance and weight loss. However, these parameters are frequently inaccurate or not collected and require a delay of several hours after diuretic administration before they are available. Accessible tools for rapid and accurate prediction of diu...
متن کاملRelationship of Loop Diuretic Dosing and Acute Changes in Renal Function during Hospitalization for Heart Failure.
BACKGROUND Worsening renal function (WRF) during heart failure (HF) hospitalization is an accepted correlate of poor prognosis. Loop diuretics are increasingly being considered as a potential cause of worsened HF outcomes, perhaps via WRF. However, the magnitude of worsening in renal function attributable to loop diuretics has not been quantified. METHODS This was a retrospective cohort study...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2019
ISSN: 2077-0383
DOI: 10.3390/jcm8111854